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Wagering at legalized betting outlets usually run by the tracks, management companies specializing in parimutuel wagering, or, in New York State, by independent corporations chartered by the state. Wagers at OTB sites are usually commingled with on-track betting pools. Make sure to check out our foal cams to see Diamond Creek Farm's newest addition. Trying to decide which horse to bet? Look for dropdowns in class level. Valentine's Day is just around the corner. Don't miss out on getting your loved one a t-shirt from our oldsmokeclothing collection!

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Mauro betting assina com a fox a rabbit

What's your number? Thermal management technology uses heated and cooled liquid to regulate the battery temperature and help it last longer, meaning fewer stops to recharge. It works to optimise performance no matter what the temperature outside. It was humongous even from seven miles away," McCormick said. For the week, front-month wheat is up 5 percent, itsbiggest weekly gain since July It was also financially unthinkable once other sources of funding began to dry up after I ask allparties to respect this decision," tweeted Nasheed, forced fromoffice in February when mutinying police and soldiers armedopposition demonstrators and gave him an ultimatum.

Several analysts saidthis would make Loblaw the country's biggest retailer byrevenue. He is fourth. In comes Rosberg for his drive-through penalty. He comes back out in a lowly 12th place. You very well know that shares can fall as well as rise so people do have to bear in mind the risks. Points for perkiness, ladies! Class attendees who score a bunny measurement of more than 97 percent will be personally invited to the Playboy Club London to try out to become the real deal, ears and fuzzy tail included.

Gerhartsreiter appeared unmoved by her statement and his demeanor was serenely calm throughout the minute hearing. Treasury secretary. Some Senate Democrats, unhappy about Mr. Summers's record on financial regulation and disparaging comments he made about women while president of Harvard University in , resisted his nomination. Summers withdrew from the running in mid-September. Will I get travelling expenses? No doubt McClean told him he was only some twelve miles from.

Will I get paid for overtime? As it turns out, the car wasn't rigged. New York's premium figuresannounced on Wednesday do not include these subsidies. The company claims its latest offering, a low-cost smartphone called "red rice," sold its entire first batch of , units within 90 seconds.

The New York socialite become pregnant while cheating on her husband with former 'American Idol' panelist Simon Cowell. Her son, GongChen, took over the family's Fangzi Beauty Salon business, whichhas 56 salons across China, after working there for eight yearswhen he returned from studying in London.

Have you got any experience? They needed someone to portray A-Rod as a martyr. The 'Teen Mom' star has reportedly decided to leave husband Corey Simms, the father of her twin baby daughters whom she married in October Messer decided to pull the plug on her six-month marriage after numerous fights with Simms over financial issues and their living situation, OK!

Whereabouts are you from? He is just eight points behind leader Hornish and only one marker in back of Regan Smith. Dillon has yet to win a Nationwide race this season. Harvard's average annualized return over the last two decades has been 12 percent, topping its 9. Instead, Phil Schiller continuously referred to the A7 as doing those things for you. Fast-tempo dances are not only a blast to do, but in an hour you'll torch to calories.

That's equivalent to light jogging on the treadmill, but it's way more fun! Because it was clear that only radical action could save us from total ruin," Enda Kenny, the premier who oversaw most of the three-year bailout, said at a party congress this month. Yet both men, former top officials now in their 70s and in ill health, have been held under tight surveillance since early They said the case went to court because of a public outcry over Yu's death as well as the family's doggedness in seeking justice.

Seawater surged into huts made fromcoconut palms near the beach. The scene then flashes back to a hospital nursery, where the baby is sucking on a pacifier and Teka congratulates Sheka on the birth of his child. It's unclear who the mother is. District Judge Jed Rakoff in Manhattan said it could make it easier for retailers to transact with customers, and make customers better understand the costs of making purchases with credit cards.

Jordan's foreign minister visited on Sunday in a sign of support. What do you do? The Cupertino company said it sold It also sold 3. The former high school sweethearts have two young children. Just a little timing was off. But it was good to do an array of things in the field. The drafters of the Affordable Care Act tried to spread the pain around with taxes and fees on device manufacturers, insurance companies, doctors and hospitals, even tanning salons.

But we've got to use this time as well tofind some savings and reforms, and we are talking about whatsavings and reforms we can get people to agree to," he said. Could you ask him to call me? A standard serving of wine is 5 ounces, according to the National Institute on Alcohol Abuse and Alcoholism.

But Doug Walker, an assistant professor of marketing at Iowa State and lead author of the study, said it's easy to lose track of how many drinks you've had, if you are pouring more than you realize. Alarmed by the recent aggression, Fiona Lange , the long-absent Supreme, sweeps back into town, determined to protect the Coven and hell-bent on decimating anyone who gets in her way. Paulson plays Lange's daughter. Boeinggained 3.

His tour guides peppertheir talk with warnings like "pickpockets to your right". It found 1. But his supporters have stayed in the streets, attracting violence from the authorities. As the country reels from crisis, the death toll just keeps rising. Who do you work for? Securities and Exchange Commission. Pretty normal Derek Jeter stuff. He wants to give it a shot after these seven days and see where he's at, which to me is normal Derek Jeter.

Besides having two on in the 15th, they also had the winning run on second in the 12th, when Wright grounded into a double play. They also had runners on first and second with two out in the 14th, when Byrd was called out on strikes. They stranded 14 runners on Thursday, and over the seven-game home stand, the Mets left 66 runners on base.

When she became vice chairwoman of the Fed in , she worked closely with Fed Chairman Ben Bernanke to continue that policy. The consortium included neitherstrategic players, nor other technology firms, he said. Wallace, 41, of Miramar, Fla. Ms Gillard has remained out of view since losing the leadership and apparently turned down an invitation to assist Mr Rudd's campaign.

Why did you come to? I mean, I have sex, but it's individual for each person,' she says. One quality Munn finds attractive in someone of the opposite sex is humor. Forward-looking statements are often characterized by the use of forward-looking terminology such as "may," "will," "expect," "anticipate," "estimate," "continue," "believe," "should," "intend," "project" or other similar words, but are not the only way these statements are identified.

These forward-looking statements may include, but are not limited to, statements relating to the company's objectives, plans and strategies, statements regarding the company's products and their expected performance, statements that contain projections of results of operations or of financial condition including, with respect to the MakerBot merger and all statements other than statements of historical facts that address activities, events or developments that the company intends, expects, projects, believes or anticipates will or may occur in the future.

Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties. The company has based these forward-looking statements on assumptions and assessments made by its management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate. Important factors that could cause actual results, developments and business decisions to differ materially from those anticipated in these forward-looking statements include, among other things: the company's ability to efficiently and successfully integrate the operations of Stratasys, Inc.

Readers are urged to carefully review and consider the various disclosures made in the company's SEC reports, which are designed to advise interested parties of the risks and factors that may affect its business, financial condition, results of operations and prospects. Any forward-looking statements in this press release are made as of the date hereof, and the company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Confidential data can pertain to customers, employees and the business and typically includes items like company account records, contact and address information, purchasing history, credit card and Social Security numbers and medical data. Funding has been provided for bike and scooter storage areas within local schools. Bem vindo! Prefeitura Municipal de Estreito. Facebook Google Plus Twitter Youtube. Cletus 16 de outubro de Sebastian 16 de outubro de Isidro 16 de outubro de Adolfo 16 de outubro de Dylan 16 de outubro de Gregg 16 de outubro de Dewitt 16 de outubro de Leonard 16 de outubro de Stacy 16 de outubro de Reyes 16 de outubro de Lloyd 16 de outubro de Sonny 16 de outubro de Jonathan 16 de outubro de Irwin 16 de outubro de Werner 16 de outubro de Marshall 16 de outubro de German 16 de outubro de Sydney 16 de outubro de Arden 16 de outubro de Anderson 16 de outubro de Coleman 16 de outubro de Nathanael 16 de outubro de Casey 16 de outubro de Abigail 16 de outubro de Juan 16 de outubro de Octavio 16 de outubro de Layla 16 de outubro de Fredric 16 de outubro de Moises 16 de outubro de Alejandro 16 de outubro de Emily 16 de outubro de Lauren 16 de outubro de Luis 16 de outubro de Brendan 16 de outubro de Bryon 16 de outubro de Barbera 16 de outubro de Giovanni 16 de outubro de Rufus 16 de outubro de Efren 16 de outubro de Rusty 16 de outubro de Heriberto 16 de outubro de Shannon 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de outubro de Quaker 16 de outubro de Lenny 16 de outubro de So, is Manning the Sith apprentice of Darth Elway?

We shall see…. The game appears to really be simple to me, when making a prediction. The Cardinals OL must control the line of scrimmage. Carolina has arguably the best DL in the league. If Palmer can get some time, he could have a field day with a short staffed Panthers secondary. Hopefully the field is finally up to snuff for the game. As I mentioned already, the winner of this game is my pick to win SB The Championship drought in the desert will end this season.

The unicorn is a legendary animal that has been described since antiquity as a beast with a large, pointed, spiraling horn projecting from its forehead. Which is why I came here , it knocks you own , not only to tear ass fool Hawk fans , Ablcolcm piles of shit? I get it FPS. Give him time…no reseason a religious zealot should know about the largest religious zealot theory in history.

It comes out exactly as tribe translated. It is unlikely that anyone would be able to translate that hebrew to text. The largest issue is that he is translating it to Hebrew before posting, and then shit gets lost in the weird world of the internet.

Hawks should be able to pick up a pass blocking OT prospect with their 2nd or 3rd pick. Of course, this will never happen…lol! Charlie the Greek …. At some point, you have to accept the fact that they have good players, who are well coached, within a good scheme. Good morning ska. GameDay on nfl starts at 9am but the game starts several hours later, i guess people must watch this trivel but holy cow. Pats-Panthers SB, and the Pats go back-to-back. TIGRE but with their d front 7 good secondary is just ok unless your offense is throwing from the one yard line and your qb is rw lol.

Got it. I think the panthers would have a better chance against NE for some reason. But i hope the cards win and denver. Panthers strength of schedule was very weak this season and their d is,noted for giving up lots of points in the 2nd half. They will not be able to handle the cards wrs. My wife is a denver fan, i like palmer and want to see phonix to get one, plus the trolling would be better. S-l-o-w… d-o-w-n….

I love Russell Wilson so? They dont care about a run game. They will just throw short passes all game like usual. Broncos d shuts down their run game. Charlie couldnt even get the gametime forecast right for az vs Car. I love Russell Wilson their wrs are back now retard. I love Russell Wilson oh you were informing me the last 3 days it was going to be sunny 1 hour after sunset. I love Russell Wilson so its not bs and you are blaming google?

Jive i never believe anything you say, You are asian. I love Russell Wilson also he had like 80 of those yards in ot. Its too negative. Im a positive person unlike you. DHC was desperately begging for me to say Palmer would have a yard game yesterday. Usually it just means you are down by a lot and need to throw to come back.

Mr asian i have company over for the game but i will be on during the game too. Dont worry your slanted eyes. Three inmates broke out of the mens santa ana jail. The middle eastern guy was part of a group who kidnapped a weed dispenser ownder and his girl, who was then burned with a blowtorch, had his penis cut off and bleach. They kept his. I dont want the Cards to win because there are douchebags like you and DHC in the world that I hope cry and potentially die from the loss.

Awe you poor baby. If cards win do us a favor and jump off the golden gate bridge. I think KZ got fooled by a tranny. We had a moonlight dinner in our room after the massage.. They came in and put flowers all over, and we had our own private waitress.. It was pretty badass.. Real world will forever suck, I need to win Powerball.. When I had the ultra-sound to make sure there were no blood clots in my leg after hurting my knee…the nurse was super hot.

They make you strip down to your boxers and she had to use one hand to push my junk to the side while getting the ultra sound device in my groin…. DGdub No way you came up with this on your own mike, what morning show were you watching that told you this? I told [Marshawn] to wait for his brother.

Two of the best QBs of all time. I love both those QBs but today I cheer for Peyton. His career is coming to an end and I want him to get to the Super Bowl one last time. Broncos D would shut the Cards down, look at what the Hawks did to them at home and what the Packers did….

Palmer would get ruined. It would come down to who turned the ball over less, him or Peyton. Yeah put 39 on that 1 defense in the nfl right too short? I got tofu dogs and veggie burgers on the grill …anyone hungry…I might make spinach and quinoa sale…yum…:. Yoshii — the HOF panty dropper the burgers are better in the microwave or oven than grill.

I find the grill dries them out too much. Lynch will not retire. Marshawn is not going to retire because then he would risk the Seahawks forcing him to pay back some of his bonus. Not going to happen. He earned that money and he knows it. No way he retires and lets it get spent on the fraud that cost him a ring.

I love Russell Wilson Lynch knows the Seahawks franchise tried to screw him. And no team will trade for him with that huge salary cap hit…. York me in the bum — One more time No, I died out in the last season…lost my interest. Be funny actually. No way he wants to see Edelman gobble up his blitz happy defense.

Drafting DTs then switching them to offense is not the answer. This place and FAP are enough. I really dont see the point in that. I love how announcers pretend they see stuff when its clearly the producer in their headset giving them the info. THere is someone in their headset telling them a lot of this info. Sorry camera angles are way better. Navorro lol you think you can see OL holds in person easier than a camera angle right behind the qb?

Navorro Sorry I just dont see how Phil Sims can call hands to the face on teh OL or holding via hands on the outside of the pads from his spot in the press box. Easier in person. Of course maybe not best guy to ask have bad vision. Paid money for seats. Especially baseball what else is there to do at O. So that is not distraction. I also give myself hair cuts. I cant do any styles. I just try to make sure I dont miss anything. No guard… Just use clippers and shave it down to stubble once every two-to-four weeks depending on how lazy I am….

Maybe you should just stay in Tahiti.

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TORINO NAPOLI BETTING TIPS

Her son, GongChen, took over the family's Fangzi Beauty Salon business, whichhas 56 salons across China, after working there for eight yearswhen he returned from studying in London. Have you got any experience? They needed someone to portray A-Rod as a martyr. The 'Teen Mom' star has reportedly decided to leave husband Corey Simms, the father of her twin baby daughters whom she married in October Messer decided to pull the plug on her six-month marriage after numerous fights with Simms over financial issues and their living situation, OK!

Whereabouts are you from? He is just eight points behind leader Hornish and only one marker in back of Regan Smith. Dillon has yet to win a Nationwide race this season. Harvard's average annualized return over the last two decades has been 12 percent, topping its 9.

Instead, Phil Schiller continuously referred to the A7 as doing those things for you. Fast-tempo dances are not only a blast to do, but in an hour you'll torch to calories. That's equivalent to light jogging on the treadmill, but it's way more fun! Because it was clear that only radical action could save us from total ruin," Enda Kenny, the premier who oversaw most of the three-year bailout, said at a party congress this month.

Yet both men, former top officials now in their 70s and in ill health, have been held under tight surveillance since early They said the case went to court because of a public outcry over Yu's death as well as the family's doggedness in seeking justice.

Seawater surged into huts made fromcoconut palms near the beach. The scene then flashes back to a hospital nursery, where the baby is sucking on a pacifier and Teka congratulates Sheka on the birth of his child. It's unclear who the mother is. District Judge Jed Rakoff in Manhattan said it could make it easier for retailers to transact with customers, and make customers better understand the costs of making purchases with credit cards. Jordan's foreign minister visited on Sunday in a sign of support.

What do you do? The Cupertino company said it sold It also sold 3. The former high school sweethearts have two young children. Just a little timing was off. But it was good to do an array of things in the field. The drafters of the Affordable Care Act tried to spread the pain around with taxes and fees on device manufacturers, insurance companies, doctors and hospitals, even tanning salons.

But we've got to use this time as well tofind some savings and reforms, and we are talking about whatsavings and reforms we can get people to agree to," he said. Could you ask him to call me? A standard serving of wine is 5 ounces, according to the National Institute on Alcohol Abuse and Alcoholism.

But Doug Walker, an assistant professor of marketing at Iowa State and lead author of the study, said it's easy to lose track of how many drinks you've had, if you are pouring more than you realize. Alarmed by the recent aggression, Fiona Lange , the long-absent Supreme, sweeps back into town, determined to protect the Coven and hell-bent on decimating anyone who gets in her way.

Paulson plays Lange's daughter. Boeinggained 3. His tour guides peppertheir talk with warnings like "pickpockets to your right". It found 1. But his supporters have stayed in the streets, attracting violence from the authorities. As the country reels from crisis, the death toll just keeps rising. Who do you work for? Securities and Exchange Commission. Pretty normal Derek Jeter stuff. He wants to give it a shot after these seven days and see where he's at, which to me is normal Derek Jeter.

Besides having two on in the 15th, they also had the winning run on second in the 12th, when Wright grounded into a double play. They also had runners on first and second with two out in the 14th, when Byrd was called out on strikes. They stranded 14 runners on Thursday, and over the seven-game home stand, the Mets left 66 runners on base. When she became vice chairwoman of the Fed in , she worked closely with Fed Chairman Ben Bernanke to continue that policy.

The consortium included neitherstrategic players, nor other technology firms, he said. Wallace, 41, of Miramar, Fla. Ms Gillard has remained out of view since losing the leadership and apparently turned down an invitation to assist Mr Rudd's campaign. Why did you come to? I mean, I have sex, but it's individual for each person,' she says.

One quality Munn finds attractive in someone of the opposite sex is humor. Forward-looking statements are often characterized by the use of forward-looking terminology such as "may," "will," "expect," "anticipate," "estimate," "continue," "believe," "should," "intend," "project" or other similar words, but are not the only way these statements are identified.

These forward-looking statements may include, but are not limited to, statements relating to the company's objectives, plans and strategies, statements regarding the company's products and their expected performance, statements that contain projections of results of operations or of financial condition including, with respect to the MakerBot merger and all statements other than statements of historical facts that address activities, events or developments that the company intends, expects, projects, believes or anticipates will or may occur in the future.

Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties. The company has based these forward-looking statements on assumptions and assessments made by its management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate.

Important factors that could cause actual results, developments and business decisions to differ materially from those anticipated in these forward-looking statements include, among other things: the company's ability to efficiently and successfully integrate the operations of Stratasys, Inc.

Readers are urged to carefully review and consider the various disclosures made in the company's SEC reports, which are designed to advise interested parties of the risks and factors that may affect its business, financial condition, results of operations and prospects. Any forward-looking statements in this press release are made as of the date hereof, and the company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Confidential data can pertain to customers, employees and the business and typically includes items like company account records, contact and address information, purchasing history, credit card and Social Security numbers and medical data.

Funding has been provided for bike and scooter storage areas within local schools. Bem vindo! Prefeitura Municipal de Estreito. Facebook Google Plus Twitter Youtube. 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16 de outubro de Edgar 16 de outubro de Thaddeus 16 de outubro de Demetrius 16 de outubro de Shayne 16 de outubro de Irvin 16 de outubro de Augustus 16 de outubro de Leroy 16 de outubro de Jarod 16 de outubro de Carmelo 16 de outubro de Norberto 16 de outubro de Everett 16 de outubro de Barton 16 de outubro de Jeremy 16 de outubro de Dexter 16 de outubro de Robert 16 de outubro de Lamont 16 de outubro de Esteban 16 de outubro de Berry 16 de outubro de Chance 16 de outubro de Dogkill 16 de outubro de Quinton 16 de outubro de Mike 16 de outubro de Isaiah 16 de outubro de Lemuel 16 de outubro de Fritz 16 de outubro de Winston 16 de outubro de Joseph 16 de outubro de Lindsay 16 de outubro de Erin 16 de outubro de Harland 16 de outubro de Granville 16 de outubro de Britt 16 de outubro de Kidrock 16 de outubro de Julius 16 de outubro de Willie 16 de outubro de Delmar 16 de outubro de Alyssa 16 de outubro de Edmundo 16 de outubro de Clair 16 de outubro de Spencer 16 de outubro de Burton 16 de outubro de Avery 16 de outubro de Jefferey 16 de outubro de Jeromy 16 de outubro de Thanh 16 de outubro de Tracey 16 de outubro de Isabella 16 de outubro de Daron 16 de outubro de Wesley 16 de outubro de Kelley 16 de outubro de Alfonso 16 de outubro de Cameron 16 de outubro de Freddie 16 de outubro de Rayford 16 de outubro de Seth 16 de outubro de Leandro 16 de outubro de Brady 16 de outubro de Anton 16 de outubro de Robin 16 de outubro de Allan 16 de outubro de Madelyn 16 de outubro de Tyrell 16 de outubro de Garrett 16 de outubro de Harris 16 de outubro de Pasquale 16 de outubro de Moshe 16 de outubro de Hannah 16 de outubro de Buddy 16 de outubro de Alexis 16 de outubro de Branden 16 de outubro de Mary 16 de outubro de Jordon 16 de outubro de Kyle 16 de outubro de Trent 16 de outubro de Devon 16 de outubro de Delbert 16 de outubro de Earle 16 de outubro de James 16 de outubro de Eric 16 de outubro de Rigoberto 16 de outubro de Danial 16 de outubro de Emerson 16 de outubro de Jackie 16 de outubro de Trenton 16 de outubro de Diana 16 de outubro de Ronald 16 de outubro de Linwood 16 de outubro de Hailey 16 de outubro de Rafael 16 de outubro de Bailey 16 de outubro de Jewell 16 de outubro de Dirtbill 16 de outubro de Stephen 16 de outubro de Philip 16 de outubro de Barry 16 de outubro de Graig 16 de outubro de Daniel 16 de outubro de Johnson 16 de outubro de Bruno 16 de outubro de Jeffrey 16 de outubro de Jamal 16 de outubro de Kraig 16 de outubro de Jonah 16 de outubro de Markus 16 de outubro de Julian 16 de outubro de Myron 16 de outubro de Duncan 16 de outubro de Jules 16 de outubro de Gabriella 16 de outubro de Emmett 16 de outubro de William 16 de outubro de Leonardo 16 de outubro de Anthony 16 de outubro de Chadwick 16 de outubro de Jamie 16 de outubro de Samantha 16 de outubro de Lyman 16 de outubro de Kaylee 16 de outubro de Solomon 16 de outubro de Blake 16 de outubro de Sofia 16 de outubro de Benton 16 de outubro de Horace 16 de outubro de Felton 16 de outubro de Brett 16 de outubro de Megan 16 de outubro de Andreas 16 de outubro de Manuel 16 de outubro de Erick 16 de outubro de Dro4er 16 de outubro de Shelton 16 de outubro de Jacinto 16 de outubro de Jimmie 16 de outubro de Jonathon 16 de outubro de Cornell 16 de outubro de Timmy 16 de outubro de Michael 16 de outubro de Olivia 16 de outubro de Bradford 16 de outubro de Florentino 16 de outubro de Orville 16 de outubro de Cooper 16 de outubro de Addison 16 de outubro de Theron 16 de outubro de Getjoy 16 de outubro de Grover 16 de outubro de Stanford 16 de outubro de Jarrod 16 de outubro de Milford 16 de outubro de Young 16 de outubro de Columbus 16 de outubro de Oliver 16 de outubro de Wallace 16 de outubro de Randolph 16 de outubro de Elton 16 de outubro de Friend35 16 de outubro de Thebest 16 de outubro de Benito 16 de outubro de Benedict 16 de outubro de Elden 16 de outubro de Diego 16 de outubro de Gonzalo 16 de outubro de Stacey 16 de outubro de Odell 16 de outubro de Emma 16 de outubro de Quaker 16 de outubro de Lenny 16 de outubro de Bernardo 16 de outubro de Eugenio 16 de outubro de Everette 16 de outubro de Mohamed 16 de outubro de Leah 16 de outubro de Brian 16 de outubro de Lifestile 16 de outubro de Harrison 16 de outubro de Israel 16 de outubro de Geraldo 16 de outubro de Wilbert 16 de outubro de Carson 16 de outubro de Edison 16 de outubro de Dallas 16 de outubro de Lance 16 de outubro de Freelove 16 de outubro de Johnathan 16 de outubro de Rickie 16 de outubro de Armand 16 de outubro de Gabrielle 16 de outubro de Ivory 16 de outubro de Ezekiel 16 de outubro de Joshua 16 de outubro de Roderick 16 de outubro de Lynwood 16 de outubro de Marcellus 16 de outubro de Dont worry your slanted eyes.

Three inmates broke out of the mens santa ana jail. The middle eastern guy was part of a group who kidnapped a weed dispenser ownder and his girl, who was then burned with a blowtorch, had his penis cut off and bleach. They kept his. I dont want the Cards to win because there are douchebags like you and DHC in the world that I hope cry and potentially die from the loss.

Awe you poor baby. If cards win do us a favor and jump off the golden gate bridge. I think KZ got fooled by a tranny. We had a moonlight dinner in our room after the massage.. They came in and put flowers all over, and we had our own private waitress.. It was pretty badass.. Real world will forever suck, I need to win Powerball.. When I had the ultra-sound to make sure there were no blood clots in my leg after hurting my knee…the nurse was super hot.

They make you strip down to your boxers and she had to use one hand to push my junk to the side while getting the ultra sound device in my groin…. DGdub No way you came up with this on your own mike, what morning show were you watching that told you this? I told [Marshawn] to wait for his brother. Two of the best QBs of all time. I love both those QBs but today I cheer for Peyton. His career is coming to an end and I want him to get to the Super Bowl one last time.

Broncos D would shut the Cards down, look at what the Hawks did to them at home and what the Packers did…. Palmer would get ruined. It would come down to who turned the ball over less, him or Peyton. Yeah put 39 on that 1 defense in the nfl right too short? I got tofu dogs and veggie burgers on the grill …anyone hungry…I might make spinach and quinoa sale…yum…:. Yoshii — the HOF panty dropper the burgers are better in the microwave or oven than grill.

I find the grill dries them out too much. Lynch will not retire. Marshawn is not going to retire because then he would risk the Seahawks forcing him to pay back some of his bonus. Not going to happen. He earned that money and he knows it. No way he retires and lets it get spent on the fraud that cost him a ring. I love Russell Wilson Lynch knows the Seahawks franchise tried to screw him.

And no team will trade for him with that huge salary cap hit…. York me in the bum — One more time No, I died out in the last season…lost my interest. Be funny actually. No way he wants to see Edelman gobble up his blitz happy defense. Drafting DTs then switching them to offense is not the answer. This place and FAP are enough. I really dont see the point in that. I love how announcers pretend they see stuff when its clearly the producer in their headset giving them the info.

THere is someone in their headset telling them a lot of this info. Sorry camera angles are way better. Navorro lol you think you can see OL holds in person easier than a camera angle right behind the qb? Navorro Sorry I just dont see how Phil Sims can call hands to the face on teh OL or holding via hands on the outside of the pads from his spot in the press box. Easier in person. Of course maybe not best guy to ask have bad vision.

Paid money for seats. Especially baseball what else is there to do at O. So that is not distraction. I also give myself hair cuts. I cant do any styles. I just try to make sure I dont miss anything. No guard… Just use clippers and shave it down to stubble once every two-to-four weeks depending on how lazy I am….

Maybe you should just stay in Tahiti. I am sure they like coke. Come on Peyton, you noodle-arm-2nd-generation-upright-choker-fuck! I wanna clap as you take down Brady and co.!! You picked a good time to go on Vacation.. Sounds like all is good back home….

DGdub lisa felt an earthquake that was 3. It was impossible but she said she felt it. Patriot-Panthers, and the Pats win another Chip. His skin is so thick, he gets mistaken for an albino elephant. I talk to some people by the pool for a couple minutes.. Bring it fuckers.. Greetings from the Gulf of Alaska fuckers! Go Cardinals! Like getting Green Gay and Philly next year.

DG you can lift your leg high enough to do a leg drop on someone? You must be the worlds strongest man. Those kankles should be registered as illegal weapons. Oh Mr. Dub we need to give you these weight belts for your ankles or you will never stay under — Snorkel instructor. DG is a real hawks fan, made vacation plans during championship weekend, knowing he wouldnt miss any hawk games. It would be great if todays Patriot loss was so bad, that Patriot fans call for Brady and Bellicheat to retire….

I want the Panthers to win the SB. It would be great to see a team finally win a SB. Would be great for the city. AZ can go fuck themselves in their SB drought. I wonder if Chip has contacted all of his out of work Duck players…. Check you fuckers later! I have never been to an anonymous forum, where a member is not only known, perp pictures from jail are posted, he posts one himself….

Purple 2. Magenta 3. Red 4. Go Broncos!!! Thats my grandpas team. You kept talking up Manning during hte beginning of the year when people were calling him old and washed up. Lots of folks in the NE will be crying in the snow today…. I did one of those Isidewith surveys a few days ago. The surprising thing is Trump finished 4th behind the dems.

My guess is because he wants to keep fed land in fed gov hands and he wants universal heathcare. Also surprised that Kasich was so far down on my list when I actually like him the most out of all the Republicans. Brady is in denver. He lost to Jake plummer. Lot of people gonna lose money today. It detailed the allegations, gleaned from court documents, that she leveled against him — that after the two began quarreling, Fitzgerald challenged her to a play fight.

Nazario said she swung at Fitzgerald, who then pushed her. DT got paid this offseason and his mom was finally released from 15 years or so of prison. He has been very unproductive this year.

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Beezhold et al. Karisola et al. SPT reactivity of the 6-residue mutant was completely abolished for all patients examined in the study. Based on B- and T-cell epitope mapping studies and sequence comparison of group 5 allergens from different grasses, point mutations were introduced by site-directed mutagenesis in the highly conserved sequence domains of Lol p 5, the group 5 allergen from ryegrass [ 99 ].

The authors succeeded in producing rLol p 5 mutants with low IgE-binding capacity and reduced allergenic activity, determined by basophil histamine release and SPTs in allergic patients. Two amino acid positions in the egg-white allergen Gal d 1 have been identified as crucial for IgE binding as they contribute substantially to the structural integrity of the protein [ ]. Sequence and fold analysis of members of the Bet v 1 family identified a short sequence stretch in Bet v 1, susceptible for mutations to induce an altered fold of the entire molecule [ ].

The replacement of 7 consecutive amino acids of Bet v 1 by the homologous Mal d 1 sequence resulted in the loss of the Bet v 1-like fold and a drastic reduction in binding IgE in birch pollen-allergic individuals. AIT is the only specific and disease-modifying treatment of allergy. The difficulty in preparing safe and effective vaccines from natural allergen extracts represents the main limitation of AIT [ ]. Vaccines based on recombinant wild-type allergens or recombinant hypoallergenic allergen derivatives offer the solution to this problem and have therefore entered into clinical testing more than a decade ago [ ].

Today, the structures of most of the important allergens are known and a wide array of recombinant hypoallergenic derivatives has been engineered [ ]. However, there is still a strong need for further research in the area of recombinant allergens and allergen derivatives to increase the efficacy and safety of AIT [ ].

WT, wild-type; FV, folding variant; r, recombinant; n, natural. In , Pauli et al. In SPTs on 29 patients and in intradermal injections of 30 patients, the hypoallergenic derivatives of Bet v 1 showed a reduced capacity to induce immediate-type skin reactions. The results of the first double-blind, placebo-controlled AIT study in birch pollen-allergic patients were published by Niederberger et al.

One preseasonal treatment course with the 2 rBet v 1 fragments or the rBet v 1 trimer induced protective allergen-specific IgG antibodies and resulted in the reduction of cutaneous sensitivity as well as an improvement of symptoms in actively treated patients. A significant reduction in the rise of allergen-specific IgE induced by seasonal pollen exposure was also observed. The observed reduced nasal sensitivity to natural Bet v 1 was significantly associated with the induced antibody levels.

However, the increase in Bet v 1-specific IgG levels resulted in the improvement of birch pollen-associated OAS symptoms only in 7 of 25 patients assessed after the vaccination with either the Bet v 1 fragments or Bet v 1 trimer [ ]. All groups demonstrated significant and equal improvements in symptoms, medication use, and skin test reactivity in 2 pollen seasons.

Clinical improvements were accompanied by marked increases in Bet v 1-specific IgG1, IgG2, and IgG4 levels, which were highest in the rBet v 1-treated group. It was clearly shown that rBet v 1 could replace the birch pollen extract in the AIT treatment of patients.

Interestingly, the extract-based treatment led to de novo induction of IgE against Bet v 2, the birch pollen profilin, in 3 patients. The safety and efficacy of rBet v 1 formulated as a sublingual tablet were assessed in a multicenter, double-blind, placebo-controlled study conducted in birch pollen-allergic patients [ ]. The average adjusted symptom scores were significantly decreased in comparison to placebo in individuals receiving rBet v 1 tablets once daily for 5 months.

A stable monomeric and hypoallergenic folding variant of Bet v 1 rBet v 1-FV was produced by changing the buffers of the chromatographic steps during the purification of rBet v 1 expressed in E. Thirty adult birch pollen-allergic individuals were treated with rBet v 1-FV for 10 weeks with weekly injections of the hypoallergen [ ]. Upon exposure to birch pollen in an environmental exposure chamber, a significant decrease in the total symptom score was observed. No serious adverse events occurred.

A preseasonal, randomized, controlled phase II study compared the effects of subcutaneous AIT with rBet v 1-FV or an established natural birch pollen extract [ ]. No statistical difference between rBet v 1-FV and the pollen extract was observed regarding the beneficial effects of the AIT. A study published in by Jutel et al. This randomized, double-blind, placebo-controlled study of subcutaneous-injection immunotherapy showed a significant improvement in the symptom medication score in subjects receiving the recombinant allergens compared to the placebo group.

Conjunctival provocation showed a clear trend in favor of the active treatment which was based on the pronounced development of allergen-specific IgG1 and IgG4. A randomized, double-blind, placebo-controlled, dose-ranging study was performed in 50 patients with a mixture of 5 recombinant Phleum pollen allergens [ ]. Eight patients experienced systemic reactions grade 1 or 2, but none experienced grade 3 or 4. Hence, this first, dose-ranging safety study with Timothy grass pollen allergens showed no major side effects, even in the very high dose range.

Very recently, a randomized, double-blind, placebo-controlled AIT study of grass pollen allergy using a recombinant B-cell epitope-based vaccine was published [ ]. The vaccine, called BM32, contained recombinant fusion proteins that consisted of the hepatitis B virus HBV surface protein preS domain as an immunogenic carrier and peptides derived from the Timothy grass pollen allergens Phl p 1, 2, 5, and 6. Sixty-eight patients completed the trial.

The total nasal symptom score decreased significantly, the total ocular symptom score and SPT reactions showed a dose-dependent decrease, and only a few grade 1 systemic reactions occurred. As a side effect of this grass pollen AIT, but of high interest, Cornelius et al. Although the number of vaccine recipients evaluated was small and no titers were determined, this study showed that the preS domain alone could induce HBV-neutralizing antibodies [ ]. The recombinant major cat dander allergen Fel d 1 was linked to a cell membrane translocation sequence and to a truncated invariant chain for targeting the MHC class II pathway, creating the modular antigen transporter MAT -Fel d 1 fusion protein [ ].

In a randomized, double-blind, placebo-controlled trial, intralymphatic immunotherapy with rMAT-Fel d 1 was performed on 20 patients. After only 3 intralymphatic injections of rMAT-Fel d 1 within 2 months, nasal tolerance increased up to fold and cat-dander-specific IgG4 was increased 5. This first-in-human clinical study of intralymphatic immunotherapy was regarded as safe and efficient in inducing allergen tolerance. The modified recombinant allergens were separately expressed in E. The 3 resulting cell suspensions were combined to form the rectally administered vaccine EMP with the goal of inducing tolerance to the dominant peanut allergens.

Ten peanut-allergic individuals received escalating weekly doses over 10 weeks, followed by 3 biweekly maximal doses. The rectal administration of EMP resulted in mild rectal symptoms in 1 patient and adverse reactions in 5 patients, including 2 anaphylactic reactions. Due to the unexpected frequency and intensity of these adverse reactions, to date, no further development of the vaccine has been reported by the company Allertein.

The EU-funded FAST Food Allergy Specific Immunotherapy project was aimed at developing a safe and effective subcutaneous immunotherapy for persistent and severe allergy to fish and peach [ ]. Of these 5 candidate molecules, 2 failed on hypoallergenicity, 2 on immunogenicity and stability, and 1 on solubility [ ]. Subsequently, 2 trimeric molecules were designed with all 8 cysteines replaced by serines, 1 heat-treated wild-type rPru p 3 was prepared, and 2 mutants were produced with 4 i.

Hypoallergenicity could be achieved at the cost of immunogenicity and stability. From these results, the authors concluded that Pru p 3 is a molecule that loses its immunogenicity when its structure is altered, and they decided to abandon its further clinical development. For the development of immunotherapy for fish allergy, the FAST project focused on the major allergen from carp, the highly cross-reactive parvalbumin Cyp c 1 [ ].

Hypoallergenic mutants of Cyp c 1 had been previously produced by mutating the 2 functional calcium-binding sites which are responsible for most of the IgE binding of the molecule [ 81 , 82 ]. The FAST project selected the mutant Cyp c 1, in which both calcium-binding sites had been destroyed for the development of a hypoallergenic vaccine for fish AIT.

Purified mutated rCyp c 1 behaved as a stable and folded molecule that had retained its immunogenicity and displayed, on average, a 1,fold reduction of IgE binding when tested with sera from 26 fish-allergic patients [ ]. Due to the low level of side effects and the positive immunological response, a multicenter clinical trial in 9 clinical centers in 6 countries was initiated in October The determination of conformational antibody epitopes on allergens is still a challenge, yet of high interest for monitoring the development of allergen-specific antibody repertoires during AIT.

Epitope grafting from allergens onto scaffolds of low-allergenic homologs is an elegant approach to a solution for this problem. Sera from 64 birch pollen-allergic patients were tested for the presence of chimera-specific IgE. The highly patient-specific IgE recognition profiles revealed that the IgE response to Bet v 1 is polyclonal and that the epitopes are spread across the entire Bet v 1 surface.

In the majority of patients, Bet v 1-specific IgE levels increased during the early phase of treatment, followed by a gradual decrease. IgE also showed the highest epitope diversity among the immunoglobulin classes investigated. Notably, the epitopes represented by the chimera Api-Bet-3 the C-terminus of Bet v 1 plus surrounding residues played a prominent role in the recognition of the allergen by all studied immunoglobulin classes.

Recombinant allergens have considerably advanced our knowledge of the immune mechanisms of allergic diseases as well as vastly enriched our toolbox for diagnosis and therapy. While recombinant allergens have contributed significantly to allergen standardization, diagnosis, structural biology, and epitope mapping, it is still an open issue whether and when recombinant AIT will replace extract-based immunotherapy.

There are 2 main aspects to consider, the regulatory aspects of AIT and the quality of the recombinant allergens. The European Community has not yet produced regulations for AIT with recombinant allergens that would be compelling for all member states. Likewise, position papers published by expert panels or scientific societies, such as the EAACI, are of no regulatory value.

In addition, recombinant allergens and hypoallergens will remain unavailable in many countries due to the strict regulatory criteria that need to be met. Hence, it is unlikely that novel allergenic molecules will be available in the near future for use as in vivo clinical diagnostic and immunotherapy reagents. On the other hand, the recombinant production of certain allergens still needs to overcome technological hurdles.

The absence of posttranslational modifications could result in a decrease of the IgE-binding capacity, as was shown for the peanut allergen Ara h 2 [ ]. A recent study on the expression of Ara h 1 and Ara h 2 in the chloroplasts of the unicellular eukaryotic green alga Chlamydomonas reinhardtii found that even the algal-produced recombinant allergens had a reduced affinity for IgE compared to the native proteins [ ].

Hypoallergenic variants of Ara h 1, 2, and 3 still produced frequent adverse side effects when administered to patients, resulting in the termination of any further development of a therapy for peanut allergy based on recombinant allergens [ ]. Two companies have turned to natural peanut proteins in their peanut allergy drug formulations, and they have tested an oral peanut protein formulation and an epicutaneous patch that delivered peanut proteins via the skin [ ].

For both drugs, desensitization was lost within weeks if patients terminated the treatment. Nevertheless, as the technology of the production of recombinant proteins is refined, they will become an increasingly attractive alternative to native allergens for allergy diagnostics and immunotherapy.

The authors declare that they have no conflicts of interest with respect to the information presented in this article. National Center for Biotechnology Information , U. International Archives of Allergy and Immunology. Int Arch Allergy Immunol. Published online May 4. Author information Copyright and License information Disclaimer.

Karger AG, Basel. This article has been cited by other articles in PMC. Abstract The years — witnessed the beginning of allergen cloning and the generation of recombinant allergens, which opened up new avenues for the diagnosis and research of human allergic diseases. Keywords: Recombinant allergens, Structural biology, Allergy diagnosis, Vaccine development, Allergy immunotherapy, Clinical studies. Introduction The history of recombinant allergens started with the very first publications on allergen cloning.

Recombinant Allergens in Structural Biology Almost all crystal and solution structures of allergens have been obtained from recombinant allergens. Table 1 Structures of selected allergens from prominent allergen families. Open in a separate window. Recombinant Allergens in Diagnostic Tests Although diagnostic assays based on purified recombinant allergens are spreading fast, extracts from natural allergen sources are still in wide use.

Vaccine Development The first AIT trial was reported in by Leonard Noon [ 52 ], who injected grass pollen extracts subcutaneously into grass pollen-allergic patients and thus achieved a reduction in allergic symptoms. Table 2 Mutational strategies to produce recombinant hypoallergens. Recombinant Allergen Fragments The IgE antibody response to respiratory allergens is mainly directed to conformational epitopes.

Recombinant Allergen Oligomers The concept of allergen oligomerization was realized by expressing 3 copies of the Bet v 1 cDNA linked by short oligonucleotide spacers with an open reading frame in E. Recombinant Allergen Mosaics Mosaic proteins created by genetic engineering are defined as artificial recombinant proteins designed from a set of peptides that are found in the reference protein s. Recombinant Allergens Modified by Mutations Genetic engineering of genes coding for allergens requires the knowledge of their B- and T-cell epitopes and, ideally, also their 3-dimensional structure.

Table 3 Recombinant allergens and recombinant allergen derivatives used in AIT studies. Cat Allergy, Fel d 1 The recombinant major cat dander allergen Fel d 1 was linked to a cell membrane translocation sequence and to a truncated invariant chain for targeting the MHC class II pathway, creating the modular antigen transporter MAT -Fel d 1 fusion protein [ ]. Fish Allergy, Cyp c 1 For the development of immunotherapy for fish allergy, the FAST project focused on the major allergen from carp, the highly cross-reactive parvalbumin Cyp c 1 [ ].

Recombinant Chimeric Allergens for Monitoring Clinical Studies The determination of conformational antibody epitopes on allergens is still a challenge, yet of high interest for monitoring the development of allergen-specific antibody repertoires during AIT. Conclusions Recombinant allergens have considerably advanced our knowledge of the immune mechanisms of allergic diseases as well as vastly enriched our toolbox for diagnosis and therapy.

Disclosure Statement The authors declare that they have no conflicts of interest with respect to the information presented in this article. References 1. Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases. J Exp Med. Cloning and expression of DNA coding for the major house dust mite allergen Der p 1 in Escherichia coli.

Int Arch Allergy Appl Immunol. The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease resistance response gene. EMBO J. Aspergillus fumigatus allergen 1, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins. Amino acid sequence of Fel d 1, the major allergen of the domestic cat: protein sequence analysis and cDNA cloning.

Recombinant peanut allergen Ara h 1 expression and IgE binding in patients with peanut hypersensitivity. J Clin Invest. Proteomic profiling of birch Betula verrucosa pollen extracts from different origins. Proteomic analysis of Parietaria judaica pollen and allergen profiling by an immunoproteomic approach. Biotechnol Lett. Resolution and identification of major peanut allergens using a combination of fluorescence two-dimensional differential gel electrophoresis, Western blotting and Q-TOF mass spectrometry.

J Proteomics. Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions. Clin Exp Allergy. Proteomic view of the venom from the fire ant Solenopsis invicta Buren. J Proteome Res. Cow's milk allergens identification by two-dimensional immunoblotting and mass spectrometry.

Mol Nutr Food Res. Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen Bet v 1. J Mol Biol. Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier. Structure of allergens and structure based epitope predictions. The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands. BMC Evol Biol. Aeropyrum pernix gen.

Int J Syst Bacteriol. Cupins: the most functionally diverse protein superfamily? Allergens are distributed into few protein families and possess a restricted number of biochemical functions. J Allergy Clin Immunol. Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins.

Mol Immunol. Prediction of IgE-binding epitopes by means of allergen surface comparison and correlation to cross-reactivity. Chimeras of Bet v 1 and Api g 1 reveal heterogeneous IgE responses in patients with birch pollen allergy. Enlarging the toolbox for allergen epitope definition with an allergen-type model protein. PLoS One. The conformational IgE epitope profile of soybean allergen Gly m 4. Varying allergen composition and content affects the in vivo allergenic activity of commercial Dermatophagoides pteronyssinus extracts.

Biochemical and immunological analysis of mould skin prick test solution: current status of standardization. In vitro and in vivo characterization of hazelnut skin prick test extracts. Indoor allergens: relevance of major allergen measurements and standardization. Variation in allergen content in sublingual allergen immunotherapy with house dust mites.

Recombinant spiked allergen extract. Enhancement of hazelnut extract for IgE testing by recombinant allergen spiking. Improved sensitivity to venom specific-immunoglobulin E by spiking with the allergen component in Japanese patients suspected of Hymenoptera venom allergy. Allergol Int. A recombinant Sal k 1 isoform as an alternative to the polymorphic allergen from Salsola kali pollen for allergy diagnosis.

Asero R. Looking for sensitization profiles in different populations by recombinant allergens. World Allergy Organ J. A comprehensive analysis of middle-European molecular sensitization profiles to pollen allergens. Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment. Advances in allergen-microarray technology for diagnosis and monitoring of allergy: the MeDALL allergen-chip. A pitfall to avoid when using an allergen microarray: the incidental detection of IgE to unexpected allergens.

J Allergy Clin Immunol Pract. Technological innovations for high- throughput approaches to in vitro allergy diagnosis. Curr Allergy Asthma Rep. Simultaneous detection of total and allergen-specific IgE by using purified allergens in a fluorescent multiplex array. Allergen micro-bead array for IgE detection: a feasibility study using allergenic molecules tested on a flexible multiplex flow cytometric immunoassay. A novel multipeptide microarray for the specific and sensitive mapping of linear IgE-binding epitopes of food allergens.

Pediatr Allergy Immunol. Real-life study for the diagnosis of house dust mite allergy — the value of recombinant allergen-based IgE serology. The house dust mite major allergen Der p 23 displays O -glycan-independent IgE reactivities but no chitin-binding activity.

Ani s like protein is a pepsin- and heat-resistant major allergen of Anisakis spp. Noon L. Prophylactic inoculation against hay fever. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. Long-term clinical efficacy of grass-pollen immunotherapy.

N Engl J Med. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis the PAT-study J Allergy Clin Immunol. Heterogeneity of commercial Timothy grass pollen extracts. Allergen content and in vivo allergenic activity of house dust mite extracts.

Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments. Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy. Recombinant allergen fragments as candidate preparations for allergen immunotherapy. IgE binding capacity of synthetic and recombinant peptides of the major storage mite Lepidoglyphus destructor allergen, Lep d 2.

Dissection of the allergic effector reaction. J Biol Chem. Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering. Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.

Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer. Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein. J Immunol. Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.

Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly. Hypoallergenic derivatives of Fel d 1 obtained by rational reassembly for allergy vaccination and tolerance induction.

Linhart B, Valenta R. Vaccine engineering improved by hybrid technology. Engineering of major house dust mite allergens Der p 1 and Der p 2 for allergen-specific immunotherapy. A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6.

Biol Chem. Molecular evolution of hypoallergenic hybrid proteins for vaccination against grass pollen allergy. Recombinant allergens with reduced allergenicity but retaining immunogenicity of the natural allergens: hybrids of yellow jacket and paper wasp venom allergen antigen 5s. Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes.

Eur J Immunol. Recombinant fusion allergens, Cry j 1 and Cry j 2 from Japanese cedar pollen, conjugated with polyethylene glycol potentiate the attenuation of Cry j 1-specific IgE production in Cry j 1-sensitized mice and Japanese cedar pollen allergen-sensitized monkeys. Moingeon P. Confira novidades e a sinopse de "Wall-E". Mais imagens de "Bee Movie". Desenho do "Chaves" no Cartoon Network. Destaques animados na TV paga. George Lucas fala sobre seriado "Clone Wars".

Novo curta do Pateta tem buzz positivo. Disney continua investindo em tecnologia. Shrek ganha lata de DVDs. Novo stop-motion da Disney seria "Frankenweenie". Imagi Studios apresenta imagem de "Astro Boy". Novidades de "Horton hears a Who". Novo filme do Garfield chega direto em DVD. Shrek chega ao quarto filme. Artistas posam para campanha da Disney. O que prever para o Oscar ? O coelho Oswald retorna em dezembro.

Curta-metragem do Pateta atrasa e Disney revela mais detalhes. Asterix ganha lata com 6 discos. Em fim de semana fraco "Encantada" lidera novamente. Imagens de "Speed Racer". Oscar - Academia desqualifica Chipmunks e aceita Beowulf. Um novo Roger Rabbit a caminho?

Disney divulga novo trailer de "Wall-E". Globo aposta em desenhos natalinos. Veja novas imagens de "Bolt". Disney prepara produtos de "Bolt". Disney divulga primeira imagem oficial de "A Princesa e o Sapo". Confira extras do DVD norte-americano de "Beowulf". Oscar - Confira a lista de indicados. Disney divulga nova imagem de "Up". Novas imagens de "Kung Fu Panda". Disney passa Cartoon e lidera na TV paga. Animagic completa 7 anos!

Diretor da Lucasfilm comenta "Clone Wars". Trailer dublado de Wall-E na internet. Suzuki Toshio fala sobre novo projeto. DreamWorks aposta alto em "Monsters vs Aliens". Confira trailer definitivo de "Wall-E". LA Times publica artigo cutucando Pixar. Box destaca insetos da DreamWorks. Walt Disney e brasileiros se encontraram em Mais imagens de "Speed Racer".

Viacom e MGM se unem para criar canal de filmes. Juliane Moore e Michael Phelps estrelam nova foto da campanha da Disney. Katzenberg decepcionado com investimento em 3D. Coelho Oswald em sapato brasileiro. Procura-se "Pocahontas" em DVD. Disney divulga capa de livro sobre "Bolt".

Moby Dick - o projeto perdido. Artistas da Disney publicam graphic novel. Disney e Pixar - o casamento funciona? Camiseta da Pixar promove "Toy Story 3". Confira novas imagens de "Madagascar 2". Muppets devem retornar em novo filme. Oswald agora aparece em camisetas. Seann William Scott revela mais detalhes de "Planet 51". Morreu Stan Winston - mestre dos efeitos especiais. Divulgada imagem oficial de "Where the Wild things Are". Confira novas imagens de "Wall-E". Pica-Pau aparece em rede de fast food.

Confira "Kiskaloo" de Chris Sanders. Disney e os planos na China. Confira novo site de "O Corajoso Ratinho Despereaux". Contagem regressiva para o Anima Mundi Personagem de "Up" aparece em "Ratatouille". Divulgadas novas imagens de "Monsters Vs Aliens". Confira teaser trailer de "A Princesa e o Sapo". Confira trailer de "Madagascar 2". Comic Con revela novas imagens de "Up".

Divulgada capa de novo livro de arte Disney. Disney divulga mais imagens de "A Princesa e o Sapo". Tintin finalmente ganha DVD nacional. Relembrando "Tusker" da DreamWorks. Novas imagens de "Bolt" em baralho promocional. Confira imagens de "Wild Life". Evento em Nova York traz Richard Williams. Jeanine Tesori confirma envolvimento em "Rapunzel". Universal desiste de "Tintin" de Spielberg. Chris Sanders em novo projeto na DreamWorks.

Disney divulga banner de "A Christmas Carol". Homer Simpson vota em Barack Obama. Exclusivo: confira imagens do projeto cancelado "My Peoples". Tim Burton em alta na Disney. John Lasseter escolhido o "inovador do ano". Disney divulga novo livro de arte para Hanna e Barbera explicam "como se faz". Warner revela o novo logotipo da Warner Bros. Mickey Mouse comemora 80 anos. Wallace e Gromit retornam em novo curta.

Simpsons tiram sarro da Apple e Steve Jobs. Canal Fox exibe especial de Natal dos Simpsons. Executivo explica os desafios de gerenciar a marca Disney no mundo todo. Turma do Penadinho vira desenho animado. Joe Moshier fala sobre sua carreira e passagem por "Rapunzel". Pixar libera mais uma imagem de "Up".

Academia divulga sete finalistas ao Oscar de efeitos visuais. Viacom usou personagens para pressionar Time-Warner. Nova imagem de "A Princesa e o Sapo". Steve Jobs doente? Dragon Ball Z retorna com tudo ao Brasil. Museu do Louvre exibe quadrinhos pela primeira vez.

Neil Gaiman sobre Henry Selick. Um animado Pixar que nunca foi: Monkey! Dan Fogler no elenco de "Mars needs Moms! Disney ultrapassa Cartoon Network. Cinemateca exibe animes. DreamWorks negocia acordo com a Disney.

Os filmes live-action esquecidos de Disney. Confira abertura de "A Pantera Cor-de-Rosa 2". Animagic completa 8 anos. Fox renova "Os Simpsons" por mais duas temporadas. Alan Menken e Glenn Slater confirmados em "Rapunzel". Confira novas imagens de "Up - Altas Aventuras".

Warner anuncia desenho do Lanterna Verde. Novo trailer de "Up - Altas Aventuras". Disney divulga imagens de "Alice" de Tim Burton. Confira os personagens de "A Princesa e o Sapo". Morreu o criador do Mr. Alerta geral! Tintin: uma nova forma de fazer cinema? Castelo de "Rapunzel" da Disney. Jonny Quest sem ser Jonny Quest?

Pode dar certo Disney muda logotipo de "A Princesa e o Sapo". Presidente Lula aparece em "South Park". Adaptando Tintin Chuck Jones e Kipling. Confira novas cenas de "A Princesa e o Sapo". Disney divulga trailer de "A Princesa e o Sapo". Confira nova imagem de "A Christmas Carol".

Morreu Wayne Allwine, a voz do Mickey Mouse. Walt Disney Treasures retorna ao Brasil. Maratona de "Ben 10" no Cartoon Network. Aberto novo blog de pesquisa sobre Disney no Brasil. Divulgado teaser trailer de "Toy Story 3". Animagic no Twitter. Primeiro poster de "Despicable Me". Pato Donald completa 75 anos. Que tal uma revista "Donald" para adultos? Animador brasileiro fala sobre o seu trabalho na Pixar. Miyazaki desembarca em julho em Bervely Hills. Morreu Michael Jackson Confira os bastidores de "A Princesa e o Sapo".

Canal Disney XD estreia hoje! Fox" tem imagem divulgada. E se Jeffrey Katzenberg permanecesse na Disney Mostra itinerante Anim! Bob Esponja completa 10 anos. Novo trailer de "Alice in Wonderland". Fox" tem trailer divulgado. Novas vozes e imagens de "Rapunzel". Rio negocia parada da Disney na praia. Victor Haboush Mais um trailer de "Where the Wild Things are". Morreu Virginia Davis Quais as curiosidades de "O Galinho Chicken Little"? Pixar e dinossauros.

Mais detalhes da compra da Marvel pela Disney. DreamWorks e o bom gosto. Stan Lee aprova compra da Marvel pela Disney. Mascote da Pixar se torna foco de processo. Miyazaki planeja ao menos mais dois filmes. Confira os 6 minutos iniciais de "A Princesa e o Sapo". Disney divulga trailer de "Toy Story 3". Astro da dublagem, Orlando Drummond completa 90 anos.

Nickelodeon compra as Tartarugas Ninja. Novidades de "A Princesa e o Sapo". Asterix celebra 50 anos com novo livro. Zemeckis confirma novo Roger Rabbit. Morre Herbert Richers, pioneiro na dublagem de filmes no Brasil. Veja primeira imagem de "Shrek 4". Zachary Levi fala sobre seu envolvimento em "Rapunzel".

Morreu Roy E. Disney Divulgada nova imagem de "Rapunzel". Animagic apresenta retrospectiva Disney compra parte da empresa de Stan Lee. Charles Chaplin em desenho animado. Dick Van Dyke de volta a "Mary Poppins". Obama mudou discurso por lobby da Disney, sugere ONG. Divulgada a primeira imagem conceitual de "Carros 2". Nova imagem do filme "Os Smurfs".

Disney planeja "Encantada 2". Morre Te Wei, o pai dos desenhos animados chineses. Disney suspende "A Rainha da Neve".

Твёрдо уверен, aiding and abetting the enemy treasonous как таком

Disney resgata curta antigo em 3-D. Veja novo trailer do filme dos "Simpsons". A saga das duas Sininhos. Animagic completa 6 anos! Criador de "Os Simpsons" fala mais sobre filme. Roger Rabbit em especial de TV do Mickey. Novas imagens e logos anunciados pela Disney. Donald estrela comercial dos anos Mais detalhes sobre "Enchanted". Morreu Yvan Delporte, cartunista pai dos Smurfs.

Disney apresenta oficialmente "The Frog Princess". Confira os novos trailers de "Homem Aranha 3" e "Ratatouille". Chris Sanders assina com a DreamWorks. Sonic e Mario finalmente juntos. Revelado novos nomes no elenco de "Speed Racer". Filme "" lidera nas bilheterias no Brasil. Confira o curta "Prelude to Eden". Saiba mais sobre a obra prima "O Gigante de Ferro". Tartarugas Ninja invadem a Avenida Paulista. Brad Bird fala sobre "Ratatouille".

Pica Pau chega ao DVD. Contagem regressiva para "Shrek 3". Glen Keane fala sobre "Rapunzel". Confira trailer internacional de "Os Simpsons - O Filme". Pateta pronto para retomar a carreira nos cinemas. Produtor confirma filme do "Gato de Botas". James Baxter comenta personagens de "Encantada". Chefes da Pixar confirmam "John Carter of Mars". Confira o primeiro trailer de "Encantada". Disney forma sociedade com Stan Lee.

Pixar tem novo projeto: "UP". SBT vai exibir "Naruto". A batalha das cidades Springfeld. Sharon Morrill se despede do DisneyToon Studios. Disney ressuscita projeto "Aida". Desenhos animados continuam fortes na TV brasileira. Confira a cobertura da Expo Disney Novidades do filme de "Os Simpsons".

Zemeckis e planos para "Um Conto de Natal". Confira primeiras imagens de "Beowulf". Sony Animation anuncia novos projetos. Confira mais conceitos de arte de "Wall-E". Animagic relembra os musicais Disney no Oscar. Check list: DVDs animados de Disney divulga cartaz de "Encantada". Saiba mais sobre o surreal curta animado "Destino". Confira a capa do novo box dos Looney Tunes.

Animagic apresenta a filmografia de Ralph Bakshi. Livro resgata pinturas de Mary Blair. Editor do Animagic comenta pesquisa sobre Disney no Brasil. Confira novidades e a sinopse de "Wall-E". Mais imagens de "Bee Movie".

Desenho do "Chaves" no Cartoon Network. Destaques animados na TV paga. George Lucas fala sobre seriado "Clone Wars". Novo curta do Pateta tem buzz positivo. Disney continua investindo em tecnologia. Shrek ganha lata de DVDs. Novo stop-motion da Disney seria "Frankenweenie". Imagi Studios apresenta imagem de "Astro Boy". Novidades de "Horton hears a Who". Novo filme do Garfield chega direto em DVD.

Shrek chega ao quarto filme. Artistas posam para campanha da Disney. O que prever para o Oscar ? O coelho Oswald retorna em dezembro. Curta-metragem do Pateta atrasa e Disney revela mais detalhes. Asterix ganha lata com 6 discos. Em fim de semana fraco "Encantada" lidera novamente. Imagens de "Speed Racer". Oscar - Academia desqualifica Chipmunks e aceita Beowulf.

Um novo Roger Rabbit a caminho? Disney divulga novo trailer de "Wall-E". Globo aposta em desenhos natalinos. Veja novas imagens de "Bolt". Disney prepara produtos de "Bolt". Disney divulga primeira imagem oficial de "A Princesa e o Sapo". Confira extras do DVD norte-americano de "Beowulf".

Oscar - Confira a lista de indicados. Disney divulga nova imagem de "Up". Novas imagens de "Kung Fu Panda". Disney passa Cartoon e lidera na TV paga. Animagic completa 7 anos! Diretor da Lucasfilm comenta "Clone Wars". Trailer dublado de Wall-E na internet. Suzuki Toshio fala sobre novo projeto. DreamWorks aposta alto em "Monsters vs Aliens". Confira trailer definitivo de "Wall-E".

LA Times publica artigo cutucando Pixar. Box destaca insetos da DreamWorks. Walt Disney e brasileiros se encontraram em Mais imagens de "Speed Racer". Viacom e MGM se unem para criar canal de filmes. Juliane Moore e Michael Phelps estrelam nova foto da campanha da Disney. Katzenberg decepcionado com investimento em 3D.

Coelho Oswald em sapato brasileiro. Procura-se "Pocahontas" em DVD. Disney divulga capa de livro sobre "Bolt". Moby Dick - o projeto perdido. Artistas da Disney publicam graphic novel. Disney e Pixar - o casamento funciona? Camiseta da Pixar promove "Toy Story 3". Confira novas imagens de "Madagascar 2".

Muppets devem retornar em novo filme. Oswald agora aparece em camisetas. Seann William Scott revela mais detalhes de "Planet 51". Morreu Stan Winston - mestre dos efeitos especiais. Divulgada imagem oficial de "Where the Wild things Are". Confira novas imagens de "Wall-E". Pica-Pau aparece em rede de fast food. Confira "Kiskaloo" de Chris Sanders. Disney e os planos na China. Confira novo site de "O Corajoso Ratinho Despereaux". Contagem regressiva para o Anima Mundi Personagem de "Up" aparece em "Ratatouille".

Divulgadas novas imagens de "Monsters Vs Aliens". Confira teaser trailer de "A Princesa e o Sapo". Confira trailer de "Madagascar 2". Comic Con revela novas imagens de "Up". Divulgada capa de novo livro de arte Disney. Disney divulga mais imagens de "A Princesa e o Sapo". Tintin finalmente ganha DVD nacional. Relembrando "Tusker" da DreamWorks. Novas imagens de "Bolt" em baralho promocional. Confira imagens de "Wild Life". Evento em Nova York traz Richard Williams. Jeanine Tesori confirma envolvimento em "Rapunzel".

Universal desiste de "Tintin" de Spielberg. Chris Sanders em novo projeto na DreamWorks. Disney divulga banner de "A Christmas Carol". Homer Simpson vota em Barack Obama. Exclusivo: confira imagens do projeto cancelado "My Peoples". Tim Burton em alta na Disney. John Lasseter escolhido o "inovador do ano". Disney divulga novo livro de arte para Hanna e Barbera explicam "como se faz".

Warner revela o novo logotipo da Warner Bros. Mickey Mouse comemora 80 anos. Wallace e Gromit retornam em novo curta. Simpsons tiram sarro da Apple e Steve Jobs. Canal Fox exibe especial de Natal dos Simpsons. Executivo explica os desafios de gerenciar a marca Disney no mundo todo. Turma do Penadinho vira desenho animado. Joe Moshier fala sobre sua carreira e passagem por "Rapunzel". Pixar libera mais uma imagem de "Up". Academia divulga sete finalistas ao Oscar de efeitos visuais.

Viacom usou personagens para pressionar Time-Warner. Nova imagem de "A Princesa e o Sapo". Steve Jobs doente? Dragon Ball Z retorna com tudo ao Brasil. Museu do Louvre exibe quadrinhos pela primeira vez. Neil Gaiman sobre Henry Selick.

Um animado Pixar que nunca foi: Monkey! Dan Fogler no elenco de "Mars needs Moms! Disney ultrapassa Cartoon Network. Cinemateca exibe animes. DreamWorks negocia acordo com a Disney. Os filmes live-action esquecidos de Disney. Confira abertura de "A Pantera Cor-de-Rosa 2". Animagic completa 8 anos. Fox renova "Os Simpsons" por mais duas temporadas. Alan Menken e Glenn Slater confirmados em "Rapunzel". Confira novas imagens de "Up - Altas Aventuras".

Warner anuncia desenho do Lanterna Verde. Novo trailer de "Up - Altas Aventuras". Disney divulga imagens de "Alice" de Tim Burton. Confira os personagens de "A Princesa e o Sapo". Morreu o criador do Mr. Alerta geral! Tintin: uma nova forma de fazer cinema?

Castelo de "Rapunzel" da Disney. Jonny Quest sem ser Jonny Quest? Pode dar certo Disney muda logotipo de "A Princesa e o Sapo". Presidente Lula aparece em "South Park". Adaptando Tintin Chuck Jones e Kipling. Confira novas cenas de "A Princesa e o Sapo".

Disney divulga trailer de "A Princesa e o Sapo". Confira nova imagem de "A Christmas Carol". Morreu Wayne Allwine, a voz do Mickey Mouse. Walt Disney Treasures retorna ao Brasil. Maratona de "Ben 10" no Cartoon Network. Aberto novo blog de pesquisa sobre Disney no Brasil. Divulgado teaser trailer de "Toy Story 3". Ronald Jones, one of the doctors who saw the throat wound before the tracheotomy, that the wound in the throat , if it is an exit wound, was created by a missile moving at a very slow velocity.

That bullet struck JFK in the back, slowed down significantly as it passed through the president and exited his throat at a very slow velocity. That bullet looks exactly like we would expect a bullet to look if it passed through a dense body, did not hit anything hard while slowing down significantly. The Zapruder film corroborates both the testimony of Dr. Ronald Jones and the existance and condition of CE Here is Dale Myers animation. And here are the frames from the actual Zapruder film which show exactly the same thing.

From the animation you should now know what to look for. And here is a link to the testimony of Dr. By the way, one should add here the discoveries about Oswald are also very important. I tried to incorporate this into my two chapters on Oswald in Destiny Betrayed. The Paines emerge from this new work as suspicious characters themselves.

I should add here, although some of this is new, some of it was in the HSCA volumes. Including the fact that the CIA did not open a file on Oswald until a year after his defection. I guess since that stuff was not in Marina and Lee, Jean did not think it was important. Yet it is. Which is why its so obsolete today. I wonder, does she acknowledge any of this is important to the Oswald case today? Would she change anything in light of these new discoveries?

I have taken this up with a specific question to Jean about one of the authors she sites as interviewing Oswald in Russia, who was then later to be found compromised by the fact that she became an asset of CIA.

This info was available from the ARRB, but as you say, Jean seems to have no interest in addendum in correcting her old irrelevant information. Frazier, made so many mistakes in his testimony to the Warren Commission in , I am almost believing he had a guilty conscience, and wanted us to see through the charade that was the coverup. I am currently writing a thread at the DPF, with the aid of a Mr. Drew Phipps of Texas, that takes a very critical look at the ballistic evidence Mr. Frazier gave to the WC, following test firings of C It should prove to be a lot of fun, and the reader should come away with a whole new perspective on just how remarkably easy it was for the FBI to fool the American public.

As far as I know, and I have been known to be wrong before, no JFK researcher has looked at the assassination from this perspective before. Bruce, do you believe that book is the strongest one showing LBJ was behind the assassination? Probably the best new evidence in the Kennedy assassination. The author ties together the evidence proving that only Lyndon Johnson had the means, motive and opportunity to mastermind the murder of President Kennedy.

No single group could have pulled off the assassination. Once the spooks, the Chiefs, the mob, the Cubans, the Texans etc. Listen to some speeches and interviews of historians, politicians and authors on youtube. The answers are out there. The most important new evidence AARB, so not that new and the least complex to understand was the release of the Parkland medical testimony, and the release of the Bethesda testimony.

Even Dr perry, cited as a defender of the headwound myth, is revealed as an unwilling participant in the cover-up. The general public are not aware, because of the delay in the revealing of this fundamental fact, how significant it is. Looking back, I marvel at the effort needed to suppress this information, but its all public now.

The wounds in both the photos and X-rays show this wound in the Occipital-Parietal! The entry wound was at the right Temperal-Parietal. A hit from a bullet travelling at super-sonic speed. Such a shot will bring a sonic shock-wave behind the bullet as it travels through the brain.

This literally explodes the tissues, purees and displaces it outward. The over-pressure taking place inside a closed container, the skull, is fragmented — not as per bullet trajectory, but as a radial blast caused by the shock wave. This particular hit was tangential, entering the right temporal area at an angle causing a trough through the right hemesphere, thus the explosive damage blew the brain material upward and slightly to the left.

These results are seen clearly in the photos and X-rays from the autopsy. This is a major mistake in doing this kind of work —. As you know, the technological progress in this area sound processing and speech recognition is almost dizzying. Notice below the spectrogram corresponding to the first seconds of the restored audio. We can clearly see that some artificial too perfect and rectangular to be natural regions were excised. As you properly indicated, once some sound fragments have been removed, they cannot be put back.

That said, I am sure that the original material is out there, so other folks, like you and me can take a crack at it, with the advantage point provided by newer tools which are being made available to the general public. This is simply not true. The original waveform is always available to test your sound reduction wave form to. I have done digital recording for at least 15 years. Jim Garrison did bring it up and Pierre Finck testified that a military ordered Dr. Hume not to dissect the wounds 2.

Joseph J. She was the wife of the golden boy of Cappucci, Lt. William Henry Amos. There are several significant discoveries made recently with regard to the murder of the 35th President. One was the discovery of by Leroy Blevins Sr. We could go on and on, but it is almost redundant at this stage. Blevins as a source? The guy who claims that shots were fired? This is nothing but unsubstantiated claims by individuals with no independent expert verification. How about Gen. Fletcher Prouty and Gen.

And Lansdale was not just any CIA operative; he was a long, notorious and highly influential and active one at that. As for Prouty, his suspicions he admitted were generated when reports he read in a New Zealand newspaper were dated such that he concluded that there was forewarning of the assassination.

He completely forgot about the International Date Line- pretty bad for an expert in intelligence. What would you claim about the veracity of an individual who claimed that he personally flew Chou-En-Li to Terehan? A guy who claimed that the JCS had foreknowledge of the Jonestown massacre and that it was a large government operation?

A guy who claimed that Roosevelt was poisoned by Churchill? You folks love to claim that this fabulist was some kind of expert on everything, when the facts are that he was a character who loved publicity and would say outrageous and unsupported things for that publicity.

Again, the CTer reluctance to ask the simple questions that shred the narrative. What utter tripe Photon, Prouty was surprised by all the info on Oswald in that NZ newspaper that on the very day of the assassination. And we have gone over that issue here, and how there was a central source that had the same story printed all over the world.

He was a VIP pilot in that era. Prouty claimed there was some evidence that Roosevelt was poisoned by Churchill, and he revealed what that was. He did not claim he was convinced of this. There is a whole school of thought that challenges petroleum as a fossil fuel. As far as Landsdale, both Prouty and Krulak knew the man intimately for decades. Landsdale did have a distinctive shape to his head, and posture, the twisted wrist, and his style of hair and dress.

Prouty was widely learned on a great many topics. He was curious and autodidactic. He did not shy from controversy, and he did not go along to get along. He was just the kind of person, that people like you love to hate. So you rely on Court Historians for reinforcement, to tell you over and again the myths you grew up with. You are in essence a shrink-wrapped prefab sprout. Krulak identified Lansdale through detail such as a stooped posture and a class ring. Prouty was not confused by an International Date Line — he was at breakfast when news of the shooting broke and several hours later picked up the local paper as it hit the streets.

It remains suspicious. Prouty never claimed to fly Chou-En-Lai anywhere. He always talked about flying a delegation of Chinese officials designated by Chiang Kai-Shek to Teheran in , where they attended a major post-war planning conference, during which decisions were made concerning Indo-China. His point always was that there was very little confirmation in official histories of the presence of the Chinese delegation. This is a false John McAdams talking point. Interesting you bring up Lansdale in Dealey Plaza.

Great post jeffc. Thank you for your always important comments Photon. I asked you on another JFK facts thread a question. You may have missed it. I would dearly love you to answer, as it is very relevant to a thread on New Evidence:. What is the official line on the assassination in ?

You represent an official viewpoint but the official viewpoint is fractured On-going New Evidence of this comes to light pretty regularly. Please could you confirm what the consensus official viewpoint is in your judgment. I noted at least 3 glaring errors the supposedly knowledgable Prouty made that no real expert on the flight would have said.

He makes stuff up. If he lied here,why believe anything he says. I learned a long time ago, that even the village idiot has somthing to contribute. Blevins is way off on most of his off-camera assertions as he is no rifleman that would understand why the shooting from the TSBD does not align in any way with the wounds to JFK or Connolly , but the shot hitting JFK in the back of the head at frame is concrete this is also one frame after Connolly is struck in the wrist.

That type of precision might be the work of a sniper given more time, but not a marksman like Oswald in less than 8 seconds, and especially not from that position where it is claimed he shot from. There was definitely more than one shooter and this was a deep state event of massively varying magnitudes targeting the seizure of power that JFK could not be allowed to wield over that deep state. Please tell me Mr. As head of the HSCA they should be considered as such.

He was Attorney General……. The work of Doug Horne is the most important assimilation of evidence in the history of this case. Anyone who sits through his six hour video presentation should feel the same way. I sat through it, and I certainly do NOT feel the same way. I think Horne is a charlatan, blending fact with fiction, and in the process leading the research in circles. The information he gives that is factual is already well known.

This presentation is more like a sermon at a revival tent. His delivery is patterned in the same hypnotic tones as neurolinguistics and faith healers. Care to give any specifics in place of personal attacks, or are you just going to carry on with this weird poetry? The Kennedy Family were entitled to that by law.

But perhaps it remained a State Secret for over 50 years. Also more than one shooter and therefore a conspiracy. For me the passage of time has given us the most important piece of new JFK assassination evidence. WE now know who where the liars, what was their agenda and with the passage of time we even know the next President of USA Bush or Clinton.

Hopefully, someday in the not-too-distant-future, Dr. Robert Blakey will get his answer from Dr. Other than that…the WC did the best it could to a. Solve the assassination albeit while protecting CIA duplicity in trying to kill Castro and b. Beyond that, I think that it has been fairly established that the Warren Commission had a direct mandate to find Lee Harvey Oswald to be the sole assassin, and that such a finding was made despite all of the evidence to the contrary.

The crime was punished. The following seem important to me in debunking the Warren Report:. This is best showing by viewing frames in pictorial and slow-motion video sequence. Boswell copped out of explaining further in his Commission testimony.

Leroy Blevins, Sr. No trajectory above ground explains that shot except a shot taken at street level. That slightest of crouching reactions likely just beginning to occur as the limo emerged from behind the freeway sign before the first head shot to what I believe was a frontal throat shot is what may have caused one of the shooters to miss his mark at the head shot resulting in denting the chrome. That miss left another shooter to have to make the shot from a higher trajectory as I believe all the shooters knew who were taking which shots and who were taking contingency shots in the case of misses.

This was no wild turkey shoot. Each shot was a coordinated shot with a purpose and each shot that was designed to hit was accompanied with a back-up plan should the target be missed. According to Blevins, the shot came from the side in the pergola area behind Zapruder. I am assuming you are new to this blog, so I will offer you some advice as per the Zapruder film.

If you are going to have an opinion on it I suggest you learn something of film emulsion chemistry, movie making machinery, and the techniques of special effects cinematography. It is suggested that you actually read what Roland Zavada explains as put forth in the article.

There was at least one other Oswald who witnesses came across in Moscow. Nevertheless, thanks to his eye-opening find in frame and of the shooter on the roof of the County Court Records building, I do believe Leroy Blevins, Sr. There have been entire books of opinion written such as the Warren Report. In many MANY local, state, and federal investigations there are people who are questioned by authorities.

The authorities, in order to protect those who are mentioned by name and who are only guilty of being in the wrong place at the wrong time, often keep these people out of the official investigative report. Police reports are full of information that may have no relationship to a particular crime and, if the names of some of the people were released some of these people may be subject to vigilante justice.

Samuel Mudd is a name that I can think of at this time. Perhaps you should look it up and not sit back like you rule over this forum. You keep making claims here that have been decisively dealt with. If you want to deal with generalizations and quips, which is all you have offered yet, but for that opinion of Oswald that is the result of a frame up by illegitimate authority, then there you have it back in kind.

He did not leave with it and coincidentally a make shift package was found on the 6th floor. A movement was seen on the Hughes Film which depicted that Limo crossing directly under the the window the rifle was fired from. Workmen heard three shots and recognized that a gun was being fired from directly above their heads.

Do you like it? I think not. Oh no! That seems well within the capabilities of the photo experts in For one, Willy, so many people have said that the limousine came to a complete stop but this is not shown in the extant film. I have also seen illustrations that compare photos and the film that show bystanders positioned differently and distortions of perspective in the film making it evident that there was more than just deletion of frames. Heck, Willy, you have the CIA photo expert who first worked on the film telling the ARRB that the film he worked on was different than the one that was released to the public.

And not only that but another CIA photo image employee did similar type work on the film the next day. Obviously, this second employee worked on the altered version. And can you tell me why the CIA needed to work on the film? Of course, there is an obvious answer to why the CIA had it.

To make sure no one saw what actually happened. Well Tom, I am a film expert, I worked in special effects cinema almost my entire adult life. Therein you will find out why one cannot use artificial light to to film Kodachrome II, and produce an undetectable counterfeit of the Z-film. Film expert, you? So is my brother he went to the movies twice a week for 8 years. Your experience as an optical film printing lab technician, matte artist, glass artist is?

Face it. Sadly, since the 3 were not communicating much like the NSA before little piss-ants like Oswald were able to pull off the assassination simply by being in the right place, with the right mentality, at just the right time. Purchased by MO with an alias LHO had used before, with handwriting linked to him through 3 different sources from multiple periods of his own life.

With an Alias his wife spoke about afterward. Among 3 spent shells.. You mean the curtain rods inside the bag tucked under his arm pit and cupped in his hand? Oh boy. Especially since Oswald was working when it was mailed across town?

Who did pick up the rifle at the post office? Where is the required postal form for picking up a firearm, supposed to have been kept on file for what two years. And on and on. BTW, have you heard? Obviously you have no recollection of AirMail. Oh yea!!! Yea I used Airmail lots of times. I could get a letter to someone by the next day…with a lot of luck.

But I never experienced getting a letter off, and a reply within a single day… and YOU? So Oswald, who was at work, got an airmail letter off, and it arrived on the same day, and then the check in that letter, was sent — by airmail of course, and arrived at the bank, on the same day! Technicality Willie but it was a Postal Money Order. A numbered one. From a series the rest of which were not used until late Not the Kansas city postal facility where unpaid Dallas money orders were stored.

Your right about Air Mail. PLEASE put to rest for all of us that the CIA and the FBI and the DPD did a thorough and accurate and complete investigation of the murder of the most powerful man in the free world by providing us with a reliable explanation why authors such as Shenon and Warren investigators like Slawson have said—all within the last year—that the CIA and the FBI withheld, suppressed, distorted, and misled the investigation at every turn?

Surely, Photon, you remember honesty? The honest answer is that the CIA and FBI knew more about Oswald than they volunteered, but not as much as they should have; they never recognized him as a potentially dangerous individual. In addition, the CIA was striving to protect sensitive intelligence sources, such as the surveillance techniques at the Cuban Embassy.

How do you think they got that intelligence? Somebody at the Embassy had access to conversations that took place there; as soon as this info came out that individual was compromised and that conduit for information ceased.. You are being disingenious when you say that they knew much more than they volunteered.

Let me repeat what you and I have already discussed. He knew how to play the game, and he played it well. He was a fraud when he started, and he remained a fraud until he died. Imagine being able to keep your job ONLY because you had illegally obtained pictures of people having sex! So, he replaced him with a drunken bozo, Angleton. I believe that to be hypocritical of you. But you can rest easy knowing that you helped create a government that continues to function on lies. Please be specific about what aspect of the JFK assassination these institutions lied about.

You keep making these blanket statements without any supporting evidence. That was truly a heavy price to pay merely to find out that Oswald wanted to go to Cuba. And what specifically did the DPD lie about? Obviously they thought that cooperating with the press might keep them from asking how they failed to protect the President. That seems a common trait among the CT community. Sometimes somebody just f—- up-a prime example being Agent Hosty.

Photon trusts the credibility of James Jesus Angleton, the man who gave away an untold number of secrets to Communist traitor Kim Philby, causing the death of dozens or hundreds of agents and Soviet moles.

Yeah, the same Angleton who did untold damage to national security and died telling people he was going to his grave with secrets. A drunken lout who thought he was above the law. Here is one for you. David Slawson, on this site, said the WC did the best it could with the information it received. He continues to say that he now knows he was naive and that the CIA withheld information that would have changed his outlook. Care to actually answer that question directly?

If you do answer that one, then we can proceed to Morley and his book, and from there we can talk about MC and the evidence that was destroyed, changed, not given, manipulated, etc. The chain of custody for CE is simply nonexistent.

He is nailed red-handed. Even your reference to agent Hosty is more than likely a LIE. It all depends on whom you believe. It was Hosty who had reopened the file. According to you, Photon, Hosty f—— up. That sure does not sound like a Hosty f—— to me. Remind me, Photon, who was in charge of the FBI in 63?

Oh, yes, I remember, J. Now, Photon, do you believe Hosty, who might be trying to cover his ass? A lot of innuendo , but nothing specific. Just one. I am not going to play your game anymore unless and until YOU answer my questions about what Hosty said about his own employer, the vaunted FBI.

Who lied? About what? Then there is little nugget from Mr. Six weeks later, the man whom they were writing about allegedly killed the president of the United States. Helms and his colleagues concealed their knowledge of Oswald from investigators.

Instead of losing his job, he served another decade. He died in October This comes from Mr. As you are well aware, Mr. Blakey has FAR more knowledge and insight into this case than you or I. Care to explain what he is saying? Here is his quote:. Had the commission known of the plots, it would have followed a different path in its investigation.

The Agency unilaterally deprived the commission of a chance to obtain the full truth, which will now never be known. We also now know that the Agency set up a process that could only have been designed to frustrate the ability of the committee in to obtain any information that might adversely affect the Agency. Many have told me that the culture of the Agency is one of prevarication and dissimulation and that you cannot trust it or its people.

End of story. Anyone interested in pursuing this story further should consult the reporting by Jefferson Morley of the Washington Post. See, e. Of course, you can stick your head in the sand and hope for the best, but I prefer to look at an issue objectively. For example, if Al Capone wanted to give me advice on how to be a good neighbor, I would probably be a tad skeptical. Likewise, if an agency that has overthrown foreign governments in the recent past tells me that they are telling all they know about an assassination of this magnitude, I would, again, be a tad skeptical.

Maybe this one will be the one that helps you understand how lying happens? I am pretty sure that does qualify as lying, but I curious as to your take on this quote. I remember a house in the country with two mail boxes. It was Postal Form as noted in this article. You have been had. I requested a reputable source-John Armstrong is a two Oswald conspiracy advocate with no credibility outside of the CT community. Can you provide a source? I know form is for gun dealers. Another interesting discussion on the subject from a few years back.

You and many CTers have brought this subject up-the least you could do is get your facts straight. You claim that Form covers all firearms. Prove it. Not with conspiracy sources nor the Education Forum, but real evidence. Until You can prove that this entire claim is a myth,just like the Hathcock myth, just like the inaccurate and inadequate Carcano myth,just like the Beverly Oliver myth,or the Judy Baker myth or the Adele Edisen myth.

Why do CTers have to resort to myths and made-up stories to bolster their case? Somewhere on this site Jean Davison covered this issue and gave a source. Remember reading it and checking. The Official Story simply assumes his possession. The postal money order was never cashed. And so on…. Lee Oswald could not have had C delivered to him. WC Exhibit No. This document is unequivocal proof from the FBI that the only authorized mail recipient at was Lee Oswald.

Claim 12 on the bottom left of the left facing page. The Warren Commission lied through its teeth in order to make Lee Oswald the guilty party in any way it could. It WAS known, and their own evidence shows that they knew it. There is nothing ambiguous about the FBI wording. It clearly states that only Lee and no one else could receive mail there.

Coupled with the fact that no postal employee ever remembered delivering a package of any sort to the PO Box, let alone one large enough to contain a rifle, it conclusively shows that the entire FBI story of the rifle was a fabrication. The record that you say shows Oswald busy at work when the rifle was picked up was a time sheet filled out by Oswald himself. Armstrong, right? Researchers have pointed out many anomalies in the record but never explain what they think happened.

IMO, if these anomalies are meaningful they should reveal a narrative that makes sense. The serial number of the rifle shipped is the same as the one found in the TSBD. Did someone find and substitute a rifle of a different length with the same serial number?

What would be the point of that? Page 50, Section Postmaster at the office of delivery shall require addressee …to call at the Post Office and establish identification to the satisfaction of the Post Master. The parcel may then be delivered after the addressee signs a receipt which shall be filed by the Postmaster for not less than three years. Manufacturers an dealers were exempt.

However, section H on the same page confuses the issue. So, it was illegal to mail a pistol or revolver to anyone other than the Military or FBI? If you skip through page 52 and Switchblades and Motor Vehicle master keys to page 53 you find: Notice of Delivery of Firearms, of the name and address of the addressee of such parcel.

One copy of this record shall be supplied to the chief law enforcement officer for the community specified in the parcel address. The third copy shall be furnished to the Postal Inspector when and requested by such service. Postmasters are also authorized to disclose these records of firearm deliveries to any Federal or State law enforcement agency upon request therefore. So it was for the pistol and for the rifle, both required to be kept on file.

Thanks again Jean. Jean, are you lost? Oswald missed time at work supposedly to get the Postal Money Order to Order it, not to pick it up. It sounds as if the FBI asked someone at the P. So what happened, then? We have been pointing this out for a long time here Jean, you just worked yourself into your own corner on this issue. Oswald ever having possession of that rifle is an ever dwindling possibility the more one looks into this.

Look for the date at the very end of that section. What stands out here is that he is not just punching a clock in and out — he is doing specific piece work which required the time expended to be noted for billing purposes. On the morning in question Oswald does nine jobs between 8 AM and None of these jobs takes him longer than 40 minutes. I consider this the most likely explanation primarily because no one has ever provided a plausible alternative explanation for the evidence that exists.

If the WC narrative is wrong, what did happen? Did someone else order and pick up the rifle, forge the BY photos, get Marina to lead cops to the empty blanket in the garage, etc.? I would like your help with this issue, as you and others have far more knowledge about this than I do. If Oswald had a P. I guess here is the bigger question. Is there such a person on the official record as saying something similar?

Any evidence you could provide would be most helpful to me. Okay, Jean. According to your proposal, that would be the only job he would have to somehow fudge. Would he be able to do it? Corresponding questions: why would Oswald take that risk late for work, presenting incorrect time sheet?

The reason there is still an argument about these things is because the original investigation was woefully inadequate. The Dallas stub should have allowed investigators to determine exactly when it was purchased. Needless to say, the Dallas stub is not in the record and never was in the record.

Holmes never produced it. The Dallas paperwork would have established the facts on the Dallas end, but it was not produced. The money order found in Washington has the initial of the post office employee who handled the purchase, but this employee was never identified or questioned — the official story says simply no one knows who handled this transaction. Other than Marina, not a single person ever saw Oswald with a rifle in How realistic is it to expect workers in a large P.

Not very, imo. He usually used the city buses. Furthermore, I am curious as to why no one from the WC or an investigator did not visit this PO and ask questions. However, it seems to me that, at the very least, someone from the WC would have taken the investigation a step further and actually visited the PO.

To me, it speaks to a general lack of thoroughness on the part of the WC. I appreciate your response on this matter. And it has not been proven beyond reasonable doubt that Oswald had an ID under the Hidell name. The wallet with that ID in it was a plant at the Tippit shooting — as has been gone through here extensively. Every anomaly in this case is more plausibly explained by Oswald being set up as a patsy.

These are the only words we can trust as Oswald actually saying while in custody, the words said on camera or tape recorded by he media at the jail. I think you are spot-on with this post. Curry and Fritz were either horribly incompetent, or involved in some type of conspiracy, or both. How either one kept their job after that weekend is a testament to the complete and utter breakdown of holding anyone accountable for doing the bare minimum of what is asked of a public servant.

But Armstrong also believes that Form was required for a rifle, among other things that I know are wrong. So why should I care what he believes? How do you know that the M. And again, what is your explanation for this evidence? Apparent anomalies, however, are everywhere. If you look you will find them. It seems to me that when anomalies are actually clues, they should tell a coherent story. Here is an explanation for why that money order seemed to display an out of sequence serial number when compared to money orders Oswald had purchased at the Dallas P.

In Dallas, this practice was changed on 5 January, with new yellow tinted money orders with face amounts key punched by new Friden money order issuing machines as the money order purchase was made at the Dallas Post office. Here is the explanation for why the serial number seemed so much greater than the serial numbers on money orders purchased in December, and included as a WC exhibit.

Image of page pg 5 at link directly above displaying text that follows image link. There are many who study facts, not anomalies, that lead them to believe that Kennedy was not assassinated by a lone assassin, and from there, a conspiracy began to emerge.

Jack Ruby strolled into the restricted area without the slightest challenge. Once Oswald was dead, the investigation took on another quality: he was not innocent until proven guilty, he was the assassin and the Warren Commission was established to convince the American public of that single fact. Anomalies aside, the WC was a kangaroo court.

That is why it is unbelievable that Oswald received that rifle. The procedures for the cashing of a money order are standard and the stamps and cancellations on the document are standard as well. The FBI claims it lost all the microfilms, and the original records themselves that the microfilms were of are no longer in existence.

I am glad the record is clarified, but coming down hard on people for missing the earlier qualifier seems a bit harsh. It is one of many details. When will you apply your unreliability test to the Lone Nut canon? Not to mention the Warren Commission. As it stands, the Official Record shows that Oswald was at work the entire morning in question, and also that Oswald presumably purchased and mailed a money order to Kleins that morning too.

Should this have gone to trial, the timecard would have served as an alibi against the presumed purchase of the murder weapon. The first possibility I posited is overcome by the second and more likely probability. Would it not be realistic to expect a blue ribbon commission to conduct itself with nothing but complete transparency and integrity? For people to continue to mollycoddle a dysfunctional investigation and report that has never succeeded in securing public opinion, is beyond me, given everything that is now known.

The more thorough any investigation is, the more anomalies are likely to turn up. Did he actually fire bullets from it into the motorcade? No one really proved that he did. Best new evidence? The possible alteration of the Z film. If Z-film frames were removed or altered, anywhere in its journey, then a preconceived conspiracy to murder — not just to cover up at the highest level, had to exist. To me, that could be the hard evidence that has the highest probably of definably answering the lone gunman question.

From that, everything else could flow. The question would then arise, is it possible to remove or alter frames from a Kodachrome II film and produce an undetectable counterfeit? According to Roland Zavada it is simply impossible. Who was Roland Zavada? He was the premier expert on film chemistry and movie making machinery of the era of film.

He was the head of the development of the film stock, Kodachrome II. Why was it flown there immediately after the assassination? Certainly not for its development as that was completed in Dallas. What was or not done by the NPIC remains an interesting area for serious researchers to examine. Zavada has stated. Yes indeed, and some are correct while others are mistaken. This is hyperbole, there are limits to anything.

These limits are clearly laid out by both Zavada and Raymond fielding. These are physical realities as true as you cannot breath water. It is not a FACT, that the original extant in camera film was delivered to the center. It is an assertion made by Doug Horne, and is disputed by many others. It is much more plausible that the first day copies of the Z-film, known to be in possession of the Secret Service are the ones that were at the NPIC to be used for making the briefing boards.

All of this being said Mr Paul, you are certainly entitled to your own personal opinion. I will just say that in my opinion you have been grossly misinformed. Thank you. What was the reason for that?

Was it simply to make briefing boards? He also said that the same film was then taken from his team by the SS. Where did it go from there? Do we know? With all due respect for Mr. Zavada, I doubt that he would be privy to, or familiar with, the high level of film resources the CIA had its disposal.

Regardless, the CIA prevailed. The science and methodology of film alteration pale in comparison. Yes, and no one from either team claimed to have made a movie — but only copied still frames to use for the briefing boards. In my opinion, yes. I see no reason for them to even consider whether the film was the original or not, they had a job to perform and worked with the materials they were brought. Remember no one was asked about any of this until years later — no controversy at the time, why would they be concerned with such details?

They were the SS copies, that they took them back seems natural enough. I can only assume they went into SS evidence lockers. Horne claims that the films went to Hawkeyworks first. One can see U S Intelligence Interests were primairily being protected in This story also has a lot to do with Cuba.

More than we ever thought. I read it from a library but wish I had a copy for reference. And lastly about Oswald: I suppose nobody finds it interesting that he poses with his rifle in the backyard photos, then denies he owns one, then denies the entire PO BOX story, then buttons up on the A. Hidell Card…. The only real mystery left to solve in this case is the lie that Oswald promulgated when he was seen exiting the building.

Yet, the obvious but unasked question would be: How do you know Mr. Yet, you were seen exiting the building by the secretary of the building by no later than pm or two minutes after being stopped and held briefly by Baker. Oswald: Why did you think there would be no more work that day????? Bill I have been waiting for an answer to this question for two years. For all of the forensic evidence that CTers ignore or claim is faked, I have yet to get a credible answer as to why he left the TSBD when nobody in the building even knew that JFK was wounded, let alone fatally-except the assassin, who saw the results through the 4x scope.

The only logical answer is that he was the shooter. It is simple. It is definitive. And it cannot be refuted. And BTW, all over Dallas that day offices closed and people went home very early because their bosses realized nobody was going to be able to do any work — most of them were too upset to concentrate on business themselves. No one ever has. Now that cannot be refuted! That is perfectly okay. Oswald must have been one nutty, uneducated, deranged loner to figure out he shot and killed the president in the 8 seconds the WC claims the shooting needed, especially when it took a dullard like Curry 6 years to figure out LHO might not have been the shooter!

Kennedy for his decisions related to Cuba. Speaking of motivation of course. Why not take the next step,Leslie? Did Joe Kennedy own United Fruit stock? Joe Kennedy and the Kennedy fortune were heavily invested in the Cuban Coca-Cola franchise and lost a fortune when it was nationalized. JFK donated his Presidential salary as he was supported by the Kennedy fortune. It works both ways photon. Even a first grader would recognize that. Do you know if counterparts of Warren Caster in their respective publishing houses were required to clock in and out of Elm?

Do you know their names? Do you know if Roy Truly could account for every person who had access to the building the morning of I doubt seriously he kept tabs on his paying customers i. Leslie, it has been 3 days since you made your first grader comment.

Nobody else has come up with any explanation- not in 3 days, not in two years. This chest thumping is hilarious Photon. What you do not have is one scintilla of proof that Oswald fired those shots — nothing. Even your circumstantial evidence has broken down. Given frequent assertions on this site that memory is compromised over time, can it be guaranteed that the recall of these people was accurate, that they remembered detail?

Could some of that detail significantly alter the conclusions? Were they questioned immediately, and if not, why not? In essence, independent researchers have attempted and continue to do the job the Warren Commission failed to do. This is the context in which the TSBD business itself, at Elm, the scene of the crime, should be of interest.

I did not see anyone in the Texas School Book Depository building on the morning of November 22, , who was a stranger. Doris Fay Burns. I have had occasion to view photographs of Lee Harvey Oswald. I did not see any strangers in the Texas School Book Depository. A distinct pattern: to a person they addressed the question of Lee Harvey Oswald, and 4 out of 5 stated specifically they had not seen a stranger in the building.

The WC was not in investigative mode, it was building a case against Oswald. It is obvious that investigators were well aware from the outset that a stranger might have been in the building; 5 months later they set about to extract statements for the record diffusing the question. If Oswald was not arraigned for the assassination until the early hours of the 23rd, was law enforcement pursuing any suspects other than him between and midnight the 22nd?

Had Oswald not been the prime focus of the commission beginning December 18 when Allen Dulles provided commission members with an innocuous little booklet analyzing previous presidential assassinations , and in fact the only focus, might at least a handful of these people have given careful consideration to the events inside the building — recollection of a shadow, a noise, a movement that could have surfaced during more intense, unbiased questioning?

Contrary to investigative protocol, these statements were not spontaneously composed; in fact when read in sequence, the content is repetitive. Read the cover letter, Leslie. Rankin asked the FBI to interview everyone and ask 6 specific questions, e. The reason the individuals answered specific questions is because they were asked specific questions, and they were asked specific question …. You argue it is because Rankin said it was all he wanted to know.

This constructs a box, a safe haven, and failing to debate outside the WC box has the appearance of avoidance. The salient question in this exchange was whether or not unknown person or persons were inside the building when the shots were fired. A trained sniper for example has a skill set to include stealth movements.

Facetious remarks are an attempt to reduce the significance of the fact that these individuals were not asked for their complete recollection but rather to limit their statements to areas that served the case against Oswald. The deeper pattern here is in the deplorable tactics of the WC.

A defence attorney would have a hey day. The WC took a page from the very systems America is said to abhor. Officer Marrion entered the building within 90 seconds and found Roy Truly. They both began a search of the building. Ibid Bonnie Richey, Secretary, does not return after the shooting. Donald Baker, Clerk, does not return after shooting. Stella Mae Jacob does not return after shooting. Burnum — McGraw-Hill employee, does not return after shooting. You conclude that one of your house-mates got up at night to make him- or herself a midnight snack and was too tired to clear the table.

This, you think, best explains the scene you are facing. To be sure, it might be that someone burgled the house and took the time to have a bite while on the job, or a house-mate might have arranged the things on the table without having a midnight snack but just to make you believe that someone had a midnight snack.

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